Survey risk factors in pregnant women who suffer from hydatidiform mole and its clinical course in Alzahra hospital in Rasht from 2003-2007

Introduction: Hydatidform mole is one of the branches of trophoblastic diseases in pregnancy. Trophoblastic diseas in pregnancy is referred to special group of diseases with different invasive and metastasis types. In attention to the importance of this disease and its high incidence in Asian and African countries and scant information in Iran, especially in Guilan, this study aims to determine the risk factors and clinical course in pregnant women who suffer from hydatidiform mole in Alzahra hospital in Rasht from 2003-2007. Methods: This is a retrospective descriptive study and its sample consists of all pregnant mothers who referred to Alzahra hospital in Rasht from 2003-2007 and were diagnosed with hydatidiform mole with sonography and were hospitalized and treated. The data were collected through patient records. Results: In this study 78 pregnant mothers with hydatidifrom mole were surveyed who referred to Alzahra hospital. The mean age of women studied was 26 years. Fifty-two percent were primigravida. In (%76.9) of samples, disease was diagnosed in gestational age less or equal to 14 weeks (first trimester of pregnancy). In this study blood group O+ (%14) with positive Rh (%84) had the most frequency. Majority (%56.4) resided in villages in Guilan province. (%2.6) of mothers had the history of H.M. %10.3 of mothers had abortion that happened before molar pregnancy. Most mothers (%39.7) didn’t use contraception. The most prevalent sign was uterus size bigger than gestational age (%75). Vaginal bleeding(%74.4), anemia(%99.2), hyperemesis gravidarum (%19.2) thyrotoxicosis(%19.2 ) tecalutein cyst(%10.2) were seen in study samples. Fetal heart activity or preeclampsia was not seen in any of the pregnant women.  Conclusion: According to obtained results routine sonography in first trimester is recommended for early diagnosis and also a support center for these mothers to be established and further prospective studies to be conducted which can help early detection, decrease expenses and help the economy.